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Ongoing studies, including TOGETHER-PsA and TOGETHER AMPLIFY-PsA, are expected to generate critical real-world data on tolerability, metabolicimmune interactions, and long-term safety of this combined therapeutic approach

Given the similarity in structure between carnitine and choline, they figured that the same kind of transformation would occur into TMAO

doi: 10.1136/bmj.i2231

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It does explain why MC1R agonism became an attractive research target for phototoxicity and photosensitivity disorders